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Alagille Syndrome

Treatment-emergent gastrointestinal effects after maralixibat often mild in ALGS

Most patients with Alagille syndrome (ALGS) treated with the apical sodium-dependent bile acid transport (ASBT) inhibitor, maralixibat (MRX; Mirum Pharmaceuticals), who experience treatment-emergent gastrointestinal effects do not discontinue treatment, according to study results presented at the 6th World Congress of Paediatric Gastroenterology, Hepatology and Nutrition. In this analysis, an integrated...

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