Cardiovascular

Distinct macrophage subsets identified in pediatric cholestatic liver disease

Three macrophage subsets with distinct transcriptional signatures were identified using single-cell RNA sequencing on the human pediatric cholestatic liver, according to a study. Using live hepatic immune cells from patients with biliary atresia (BA), Alagille syndrome (ALGS), and non-cholestatic pediatric liver, researchers used single-cell RNA sequencing analysis and immunofluorescence to...