1. Sep 16, 2020

Preserving kidney function in youth may preserve cognitive function in midlife

Worse cognitive performance at midlife was associated with a decline in kidney function during young adulthood, according to a study in Neurology.

In this population-based longitudinal study, 2604 participants from the population-based Coronary Artery Risk Development in Young Adults Study were included.

In total, 16% of the study population had at least 1 episode of End Stage Renal Disease (ESRD) exposure. Higher risk episodes were linked with lower composite cognitive function, psychomotor speed, and executive function, independent of socio-demographic status and cardiovascular risk factors.

The authors concluded that “preserving kidney function in young age needs to be investigated as a potential strategy to preserve cognitive function in midlife.

Sedaghat S, Sorond  F, Yaffe K, et al. Decline in kidney function over the course of adulthood and cognitive function in midlife. Neurology. 2020; DOI: 10.1212/WNL.0000000000010631.