Six minute-walk stress echocardiography assess risk of adverse event in patients with ILD
In patients with interstitial lung disease (ILD), increased pulmonary vascular resistance (PVRecho) after a 6-minute walk test (6MWT) is predictive of cardiopulmonary events, according to a study.
In this study, 68 patients with ILD underwent echocardiographic examinations. Pressure gradient of tricuspid regurgitation (TRPG) and PVRecho were measured at baseline and at post-6MWT.
Overall, 22 patients had cardiopulmonary events during a mean follow-up period of 22 ± 12 months. PVRecho pre-and post 6MWT; TRPG pre-and post 6MWT; and %VC were significantly associated with cardiopulmonary events, in univariate analysis. In multivariate analysis using the Cox proportional hazards model, %VC and PVRecho post 6MWT were found to be independent predictors of cardiopulmonary events in patients with ILD.
Yasui K, Yuda S, Abe K, et ak. Prognostic value of 6-min walk stress echocardiography in patients with interstitial lung disease. J Echocardiogr. 2021; DOI: 10.1007/s12574-021-00532-x. Epub ahead of print. PMID: 34091856.