1. Oct 13, 2020

Case Report: Sarcoma with metastatic pulmonary dissemination mimics COVID-19 clinical features

In this case report, a 13-year-old boy with fever, dry cough, persistent asthenia and impaired general condition of 2 weeks' duration, presented to the hospital. Bloodwork showed a severe inflammatory status and X-rays were consistent with bilateral COVID-19 pneumonia. The patient developed an acute respiratory failure and COVID-19 treatment was started.

Repeated serological tests and real-time reverse transcription PCR for SARS-CoV-2 were negative and other pathogens were ruled out. An intense bilateral pulmonary dissemination with lytic vertebral bone lesions was found on a thoracic high-resolution CT scan. The patient was diagnosed with Ewing's sarcoma with metastatic pulmonary dissemination.

The authors concluded that, “In the context of SARS-CoV-2 community pandemic, we cannot forget that COVID-19 clinical presentation is not specific and other entities can mimic its clinical features.

Reference
Perdigón Martinelli C, Morell C, González C, et a. Metastatic pulmonary dissemination as differential diagnosis of COVID-19 disease. BMJ Case Rep. 2020;13(10):e237453. doi: 10.1136/bcr-2020-237453. PMID: 33028572.